So, how old are these Pre-Hispanic Cultures?

The oldest Culture known in meso and south America of Pre-Hispanic according to archaeology studies and ethno historical evidence seem to be the MONAGRILLOS of Panama who date approximately 5000 BC.

Now, let’s remember that Panama use to be part of Colombia until it got its independence before the Construction of the Panama Canal, meaning that their works of Pottery (also Colombian) in which they did not only specialized but were magnificent in still remain in most Pre-Hispanic Museums of Colombia today.
The MONAGRILLOS created the polychrome pottery technique in the Coclé region of Panama, a pottery highly desirable among Collectors.

The attached photos were taken from pre-columbianconsultants.com